Dr. Amr Elyamany

Knee Clicking, PRP and Collagen Injections, and Pain After a Run

By · · Medical Research · 2 min read

Knee Clicking, PRP and Collagen Injections, and Pain After a Run


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Three questions about knees come up all the time from people who exercise. Dr. Amr Elyamany gives evidence-based answers.

Does clicking during exercise mean the joint is healing, or is it dangerous?

Neither. Clicking is normal and happens to almost everyone. It is not a sign that something is being repaired and it is not dangerous, unless it comes with severe pain or swelling in the joint.

Do plasma (PRP) or collagen injections rebuild cartilage?

Scientifically, not so far: there is no evidence that they rebuild cartilage. But they can help by reducing friction, pain and swelling in the knee, which can be useful if you have significant discomfort.

Strong knee pain after a run: continue or rest?

If the pain is strong after exercise, rest. Put ice on the area and take a painkiller if needed, then see whether the pain disappears. If it does not go away, you need to see a doctor.

Key takeaway: Painless clicking is harmless, injections may relieve symptoms but do not regrow cartilage, and persistent pain deserves an examination.

When to see a doctor

  • Clicking with severe pain or swelling
  • Knee pain that has not gone after a few days of rest
  • Pain that returns each time you run

Need advice about your own case? Book a consultation with Dr. Amr Elyamany in Dubai.

This article is for general education and does not replace an in-person medical examination. If you have symptoms, please consult a qualified doctor.

Tags: Knee · Myths & Facts · Joint Health · Running

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